AMP4SKIN:  Antimicrobial peptide produced by molecular farming in barley and its use in the formation of skin-applicable carriers

Technology Agency of the Czech Republic
Project number: TQ03000264

Principal Investigator for UP: RNDr. Lenka Dzurová, Ph.D.

Other participant: ÚSOVSKO AGRO s.r.o., Ing. Jiří Milek

Funding: 3 851 722 CZK (UP)
Implementation period: 01/2024-12/2025

The AMP4SKIN project focuses on utilizing the recombinant human antimicrobial peptide cathelicidin in various commercially available carriers to develop creams for topical application. This peptide, fused with a protective protein domain, is produced through a patented process in barley spikes grown on the accredited experimental fields of the ÚSOVSKO company.

Planned project results:

  1. 2x Jimp – Articles in a scientific journal: A review paper in 2024 and a research paper in 2025.
  • Ztech – Proven technology: Procedure for testing the antimicrobial activity of the MBP-rhLL37 peptide in carriers for dermal use.
  • Fuzit – Useful pattern: Antimicrobial peptide carrier for dermal use.
  • O- Other Results: Poster presentation at the ECB International Conference in Rotterdam (2024) and another conference in 2025.