Consulting & Experts

CATRIN scientists evaluate both traditional and modern crop breeding methods using classical yield parameters, resistance testing under environmental stress, and advanced chemical analyses. A dedicated phytochemical analysis platform enables the quantification of a broad range of primary and secondary metabolites.

CATRIN operates Olophen, a state-of-the-art (semi-)automated plant phenotyping platform capable of analysing thousands of plants in a single experiment under combined stress conditions using non-invasive imaging approaches. Olophen is part of the Czech Plant Phenotyping Network (CzPPN), which contributes to the European ESFRI–EMPHASIS project involving 23 countries. Researchers are developing affordable phenotyping systems, including both hardware and software, to overcome current bottlenecks in phenotyping and data analysis in line with FAIR principles. Artificial intelligence and machine learning are being integrated to further enhance data processing.

CATRIN also operates a plant genetic transformation platform. Using advanced molecular biology and genetic engineering methods, researchers develop crops with higher yields, improved resistance to drought, climate fluctuations, diseases and pests, and increased levels of health-promoting compounds.

CATRIN’s research in translational medicine combines nanotechnology, biomedicine and molecular biology to address the prevention and treatment of lifestyle diseases. Scientists develop unique materials and technologies for improved diagnosis and therapy of cancer, inflammatory and infectious diseases, and rare genetic disorders. During the COVID-19 pandemic, CATRIN researchers developed iron-based magnetic particles that enable rapid isolation of RNA and DNA from biological samples. This technology is now used in diagnostic kits not only for COVID-19, but also for other viral infections. Another major research focus is combating bacterial resistance to antibiotics.

Researchers are also developing new drug delivery systems, advanced imaging technologies and plasmonic biosensors that accelerate disease detection and improve treatment outcomes. In close collaboration across CATRIN, multifunctional nanoparticles and 2D materials are designed for targeted drug delivery, tumour imaging and real-time monitoring of biological processes. Rigorous toxicity testing ensures these materials are safe for clinical and commercial use.

At the same time, scientists study fundamental biological mechanisms underlying lifestyle diseases, particularly cellular responses to DNA damage and repair. These processes are central to cancer development and represent promising targets for novel therapies. High-capacity screening systems are being developed to assess the impact of various substances on DNA integrity in human cells, bridging basic research with applications that offer strong commercial potential.

CATRIN combines advanced materials research with a vision of sustainable energy systems. Scientists develop innovative materials for the efficient conversion, storage and utilisation of renewable energy. New hybrid systems based on photoactive semiconductors and carbon nanomaterials enable the conversion of solar energy into chemical energy through processes such as water splitting and photoelectrocatalysis, supporting the production of clean hydrogen.

Another distinctive approach is the synergistic combination of strategies that significantly enhance (photo)electrocatalytic efficiency. The resulting materials feature optimised structure and functionality, improved light absorption, enhanced charge transfer and faster surface reactions—key properties for next-generation solar cells and hydrogen production technologies.

Energy storage research is equally important. Leveraging deep expertise in 2D graphene chemistry, CATRIN researchers have developed graphene derivatives with exceptional potential for batteries and supercapacitors. Nitrogen-doped graphene, in particular, shows outstanding performance in supercapacitors, offering fast charging and long service life compared to conventional lithium-ion batteries. Within the European Innovation Council TRANS2DCHEM project, carried out with Bar-Ilan University (Israel) and ITELCOND (Italy), researchers developed a prototype device with unique properties. To bring these results to market, the spin-out company Atomiver has been established.

The development of advanced materials is one of CATRIN’s strongest research pillars, with internationally recognised results. In 2010, CATRIN scientists contributed to the discovery of fluorographene, followed by the development of 2D chemistry, enabling a broad portfolio of derivatives with tunable physical, chemical and mechanical properties. These materials are applicable in biomedicine, sensing, energy, electronics and surface protection. More information is available at graphene-derivatives.com.

CATRIN has long-standing expertise in the development and functionalisation of magnetic nanoparticles. Through controlled chemical modification, researchers tailor nanoparticles for highly specific applications, ranging from biomolecule separation and industrial purification to diagnostics and analytics. Nanoparticles can be customised to partner requirements, including highly selective protein separation from complex matrices.

Successful technology transfer is demonstrated by two licensing agreements for lactoferrin separation from cow’s milk and whey, linking CATRIN’s research excellence with the needs of the food and biotechnology industries.

CATRIN applies advanced nanotechnologies to water treatment, developing systems based on reactive iron nanoparticles for wastewater and groundwater remediation. In the NANOBIOWAT project, researchers demonstrated how close cooperation between academia and remediation companies enables direct industrial application. These technologies have already been deployed at several contaminated sites in the Czech Republic and abroad.

One concrete outcome is a preparation based on iron nanoparticles designed for emergency water purification. Effervescent tablets rapidly remove hexavalent chromium, arsenic, herbicides, pesticides and other pollutants from water.

Alongside applications, CATRIN conducts fundamental research into nanomaterial interactions with living systems and their long-term environmental behaviour, including the influence of natural organic matter on water purification performance.