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CATRIN-MAT

Biologically Active Complexes and Molecular Magnets

The group develops biologically active coordination compounds and molecular magnetic materials.
Research Areas
prof. RNDr. Zdeněk Trávníček, Ph.D.
Group leader
Phone +420585634545
E-mail zdenek.travnicek@upol.cz
Profile page

About the group

The research focus of this group can be divided into two main areas.

The first is the development of new types of biologically active coordination compounds of selected transition metals, led by efforts to prepare compounds with medical application potential, such as substances with anti-tumour, anti-inflammatory or anti-diabetic effects.

Scientists are also engaged in the preparation and study of molecular magnets and molecular switches based on transition-metal complexes with application potential in sensors, high-density storage or recording media.

News

Papers
Publication in Bioorganic Chemistry
Substituted diiminoisoindoles as anticancer agents: synthesis, structural characterization, and biological evaluation Authors: Stanislava Majerová, Otakar…
News
Publication in Pharmaceutics
In Vitro Cytochrome P450 Interaction Profile and ADME Characterisation of Gold(I)–Triphenylphosphine Complexes with 6-Alkoxy-9-Deazapurine Ligands…

List of Employees

Name Academic title E-mail Phone Position
Zdeněk Trávníček prof. RNDr., Ph.D. zdenek.travnicek@upol.cz +420585634545 Group leader
Michal Čajan doc. RNDr., Ph.D. michal.cajan@upol.cz +420 585 63 4631
Barbora Komendová Mgr. barbora.komendova@upol.cz +420585634486
Ján Vančo doc. PharmDr., Ph.D. jan.vanco@upol.cz +420585634486

Group publications

V. Němec, J. Holub, M. A. Samsonov, Z. Růžičková, J. Cvačka, J. Vančo, Z. Trávníček, J. Belza, Z. Dvořák, J. Vrána and A. Růžička
"The Far Side of Carboranes: Anticancer Active Monocations and Ambiently Stable Dications",
ANGEWANDTE CHEMIE INTERNATIONAL EDITION, vol. 65, iss. 20, e21595, 2026.
IF = 17.6
CATRIN-MAT
DOI: 10.1002/anie.202521595
M. Medvedíková, J. Vančo, Z. Trávníček and P. Anzenbacher
"In Vitro Cytochrome P450 Interaction Profile and ADME Characterisation of Gold(I)–Triphenylphosphine Complexes with 6-Alkoxy-9-deazapurine Ligands",
PHARMACEUTICS, vol. 18, iss. 5, pp. 599, 2026.
IF = 6.9
CATRIN-MAT
DOI: 10.3390/pharmaceutics18050599
A. B. M. Ibrahim, Z. Trávníček and G. A. Mahmoud
"Synthesis, crystal structures, and anti-pathogenic activity of cobalt(II) and zinc(II) N-Phenylpiperidine-1-carbothioamide complexes against fusarium oxysporum",
INORGANIC CHEMISTRY COMMUNICATIONS, vol. 183, pp. 115798, 2026.
IF = 5.9
CATRIN-MAT
DOI: 10.1016/j.inoche.2025.115798
Z. Trávníček and M. Čajan
"Synthesis, structural features, and in vitro anticancer assessment of zinc(II) complexes with quinolinone-derived ligands",
STRUCTURAL CHEMISTRY, Article in press, 2026.
IF = 2.3
CATRIN-MAT
DOI: 10.1007/s11224-026-02727-3
S. Stocchetti, J. Vančo, G. Bresciani, L. Biancalana, J. Belza, S. Zacchini, Z. Dvořák, S. Benetti, T. Biver, M. Bortoluzzi, Z. Trávníček and F. Marchetti
"Anticancer diiron aminocarbyne complexes with labile N-donor ligands",
EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY, vol. 286, pp. 117304, 2025.
IF = 6.7
CATRIN-MAT
DOI: 10.1016/j.ejmech.2025.117304
A. Peuronen, P. Damlin, J. Vančo, Z. Dvořák, Z. Trávníček, A. Lehtonen
"Structural variations in copper(II) amine-bisphenolate complexes: Evaluation of in vitro antiproliferative activity against human cancer and normal cells",
Inorganic Chemistry Communications, vol. 180, pp. 115024, 2025.
IF = 5.9
CATRIN-MAT
DOI: 10.1016/j.inoche.2025.115024
All group publications