CATRIN-BIO

Crop engineering and biotechnology

Developing crop plants with improved stress tolerance, yield, and quality through modern biotechnology.
Research Areas
  • Chemistry
  • Agriculture
  • Translational Medicine
  • Renewable Energy
  • Innovative Materials
  • Nanotechnologies
prof. RNDr. Ivo Frébort, CSc., Ph.D.
Group leader
Phone +420585634922
E-mail ivo.frebort@upol.cz

About the group

The research group focuses on molecular and systems-level mechanisms controlling growth, development and stress adaptation of crop plants, with a primary emphasis on barley. Key research topics include genetic regulation of plant responses to abiotic stress, targeted modification of yield- and quality-related traits, and applications of modern biotechnologies in sustainable agriculture.

The research addresses current challenges posed by climate change and the need for stable and sustainable food production. The group employs genome editing using CRISPR/Cas9 and operates a unique platform for plant genetic transformation. A highly distinctive component of the research is the implementation of accredited field trials with genome-edited barley, conducted in compliance with EU legislation. These trials enable functional gene validation and evaluation of agronomic traits under realistic field conditions and represent a rare research infrastructure at the European level.

Another major research avenue is molecular farming in barley aimed at the production of recombinant antimicrobial peptides and antigens with applications in cosmetics and veterinary medicine. The group is also involved in a newly initiated project developing an automated bioreactor for studying barley growth and development under microgravity conditions.

Research activities are carried out in close collaboration with academic and industrial partners in the Czech Republic and abroad and are strongly integrated with other research teams and infrastructures within CATRIN.

News

List of Employees

Name Academic title E-mail Phone Position
Ivo Frébort prof. RNDr., CSc., Ph.D. ivo.frebort@upol.cz +420585634922 Group leader
Véronique Hélene Bergougnoux-Fojtik Ph.D. veronique.bergougnoux@upol.cz +420585634739
Lenka Dzurová RNDr., Ph.D. lenka.dzurova@upol.cz +420585634892
Jitka Frébortová doc. RNDr., Ph.D. jitka.frebortova@upol.cz +420585634871
Edita Holásková Mgr., Ph.D. edita.holaskova@upol.cz +420585634891
Ondřej Kocáb Mgr., Ph.D. ondrej.kocab@upol.cz +420 585 634 819
Nikola Kořínková Mgr., Ph.D. nikola.korinkova@upol.cz
Mária Majeská Čudejková Mgr., Ph.D. maria.majeska@upol.cz
Alžběta Mičúchová Mgr., Ph.D. alzbeta.micuchova@upol.cz
Hana Pospíšilová Mgr., Ph.D. h.pospisilova@upol.cz +420585634891
Vendula Svobodová Bc. vendula.svobodova@upol.cz +420585634741

Group publications

P. Kührová, V. Mlýnský, I. Frébort, J. Frébortová, M. Otyepka, J. Šponer and P. Banáš
"Toward Accurate RNA Folding Thermodynamics: Evaluation of Enhanced Sampling Methods for Force Field Benchmarking",
JOURNAL OF CHEMICAL THEORY AND COMPUTATION, vol. 22, iss. 10, pp. 5247-5258, 2026.
IF = 5.8
I. Frébort and C. Hjort
"Unlocking Innovation in European Plant Breeding: A Perspective on the New Genomic Techniques Framework",
NEW BIOTECHNOLOGY, vol. 96, pp. 163-167, 2026.
IF = 5.6
L. Dzurová, E. Holásková, H. Pospíšilová, J. Milek and J. Frébortová
"Proteolytic activation of barley-expressed human cathelicidin LL-37 by skin serine proteases",
PROCESS BIOCHEMISTRY, vol. 170, pp. 23-33, 2026.
IF = 4.4
Ľ. Majeský, M. Hroneš, M. Kitner, L. Mártonfiová, L. Vaculná, M. Majeská Čudejková, L. Kobrlová, B. J. Płachno, F. Conti and M. Dančák
"Evolutionary history of Pinguicula sect. Pinguicula (Lentibulariaceae)",
BOTANICAL JOURNAL OF THE LINNEAN SOCIETY, vol. 211, iss. 3, pp. 314-335, 2026.
IF = 2.1
P. Tarkowski, P. Kopecký, K. Riboulet-Zemouli and I. Frébort
"Where are you heading to, Cannabis research?",
PHYTOCHEMISTRY REVIEWS, vol. 24, iss. 5, pp. 3307-3314, 2025.
IF = 6.3
P. Pesaresi, P. Bono, S. Corn, C. Crosatti, S. Daniotti, J. D. Jensen, I. Frébort, E. Groli, C. Halpin, M. Hansson, G. Hensel, D. S. Horner, K. Houston, A. Jahoor, M. Klíma, H. Kollist, C. Lacoste, B. Laidoudi, S. Larocca, C. Marè, N. L. Moigne, C. Mizzotti, T. Morosinotto, K. Oldach, L. Rossini, S. Raubach, M. Sanchez‐Garcia, P. D. Shaw, R. Sonnier, A. Tondelli, R. Waugh, A. P. Weber, D. Yarmolinsky, A. Zeni and L. Cattivelli
"Boosting photosynthesis opens new opportunities for agriculture sustainability and circular economy: The BEST‐CROP research and innovation action",
THE PLANT JOURNAL, vol. 121, iss. 3, pp., 2025.
IF = 6.2
All group publications